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Although the series is set in Seattle (at the fictional Seattle Grace, later known as the Grey-Sloan Memorial Hospital), it is filmed primarily in Los Angeles, California.
The show was originally titled Complications, a double-edged reference to both the complicated medical procedures and personal lives of the characters.
Grey's Anatomy is an American medical drama television series that premiered on March 27, 2005, on American Broadcasting Company (ABC) as a mid-season replacement.
The fictional series focuses on the lives of surgical interns, residents, and attending physicians, as they develop into seasoned doctors while trying to maintain personal lives and relationships.
[...] My sisters and I would call each other up and talk about operations we'd seen on the Discovery Channel.
There's something fascinating about the medical world—you see things you'd never imagine, like the fact that doctors talk about their boyfriends or their day while they're cutting somebody open.
In Season twelve attending cardio surgeon Nathan Riggs (Martin Henderson) joins the show.
In season thirteen, the hospital sees a shakeup when attending sports medicine/orthopedic surgeon Eliza Minnick (Marika Dominczyk) is hired as an educational consultant to revamp the residency program.
Since its inception, the show has been described by the media outlets as a television "phenomenon" or a "juggernaut", owing to its longevity and dominant ratings.In the sixth season, these residents are joined by Jackson Avery (Jesse Williams) and April Kepner (Sarah Drew), former Mercy-West residents who join Seattle Grace following an administrative merger.During the first six seasons, Burke, O'Malley and Stevens all depart the series.The cast has undergone major changes through the series' run, with many members leaving and being replaced by others.In its twelfth season, the show had a large ensemble of sixteen actors, including four characters from the original cast (Meredith Grey, Alex Karev, Miranda Bailey, and Richard Webber).